These days, it can be hard to know what’s good for our bodies. When you walk into a wellness store, it’s easy to feel overwhelmed with shelves upon shelves of multivitamins and minerals.

Should I take that vitamin on the shelf? How beneficial are they? Not very, according to a new study published in Annals of Internal Medicine.

Researchers from West Virginia University and Johns Hopkins analyzed 277 randomized controlled trials and said they couldn’t find any proof that people will live longer by regularly taking any of the 16 supplements they studied — vitamins A, B2, B6, B complex, C, D, E, multivitamins, iron, selenium, calcium, calcium and vitamin D, folic acid, beta-carotene, antioxidants and omega-3.